Research Team
Our research is driven by our curiosity about fungi, their interactions with animals, and their abilities to hijack their hosts.
Through our interdisciplinary collaborations we ask research questions across levels of biological organisation.
PI: Charissa de Bekker, PhD
The natural world around us has always fascinated me: from large mammals, to small insects, to micron-sized microbes. This inherent interest motivated me to study biology. During my Bachelor studies, I thought I would specialise in animal behaviour. However, the incredibly cool tools that molecular microbiology offers pulled me away from this path. I ended up with a Masters in biomolecular sciences and did my PhD within the fungal genetics field. As a postdoc, I found my way back to studying animal behaviour through a research program that allows me to combine behavioural ecology with my, initially unexpected, fascination for fungi and molecules.
After initially setting up my lab at UCF in Orlando, Florida, I am currently an associate professor at Utrecht University in the Netherlands. My lab studies parasites that change host behaviour. One of the most dramatic examples of this phenomenon are the zombie ants. I use this fungus-insect interaction as a model system to study the fungal natural products involved in host manipulation and their effects on insect behavioural pathways. The overarching aim of this work is to elucidate how parasites can affect the behaviour of their hosts, how behaviour is regulated and dysregulated at the molecular level, and what neuroactive compounds are involved. By answering these fundamental research questions we are discovering novel bioactive compounds that can be used in more sustainable pest control approaches or have medical applications.
Meet the team
Our team consists of researchers from various backgrounds, expertises, and research interests. We strive to be an inclusive workplace where everyone can feel comfortable being their authentic selves while pursuing their personal goals and ambitions.
Postdoctoral Scholars
William Beckerson, PhD
MSCA Postdoctoral Research Fellow
William aims to characterise the functions of candidate manipulator compounds produced by Ophiocordyceps. He uses a variety of functional genetics tools and organisms in this endeavour. Additionally, William is interested in discipline-based education research in biology and involved in a variety of teaching and outreach efforts.
Joana Dopp, PhD
Joana aims to characterise the neurobiological mechanisms of extended phenotypes and in particular the ways in which Ophiocordyceps hijacks the ant’s circadian rhythm. She makes use of omics technologies, insect genetics, microscopy and behaviour assays.
PhD Candidates
Emmeline van Roosmalen, MSc
Emmeline is using molecular microbiology techniques to unravel the functions of Ophiocordyceps small secreted proteins in the manipulation of ant host behaviour.
Robin Jonkergouw, MSc
Robin is a PhD candidate in the UU Science for Sustainability Program. His research harnesses the ability of fungi that infect and manipulate insects to discover more sustainable novel pesticides.
Miriam von Bargen, MSc
Miriam aims to understand the role of protein tyrosine phosphatases secreted by Ophiocordyceps in behavior manipulation of ant hosts by applying molecular techniques, ant behavioral assays, and transcriptomics.
Maite Goebbels, MSc
Maite is a PhD candidate unveiling the identity and function of unknown Ophiocordyceps secreted proteins and their role in host behavioral manipulation. She employs different bioinformatic, molecular and microbiological strategies to elucidate this extended phenotype and study ant behavior.
Sinah Wingert, MSc
Sinah is investigating the role of Enterotoxins, a group of recently discovered fungal proteins. She uses bioinformatical methods, behavioral assays and molecular methods, focusing on establishing RNA interference as a tool for post transcriptional gene expression knockdown in ants.
Master Students
Gloria Mistri
Master Program: Environmental Biology, UU
Ray Bouw
Master Program: Molecular and Cellular Life Sciences, UU